Size

100 ug

Catalog No

29-702

Price

180€

Buy: anti-PPFIBP1 Antibody

Gene info

PPFIBP1 is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. It has been proposed that liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR family of tyrosine phosphatases. This protein was found to interact with S100A4, a calcium-binding protein related to tumor invasiveness and metastasis.The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. It has been proposed that liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR family of tyrosine phosphatases. This protein was found to interact with S100A4, a calcium-binding protein related to tumor invasiveness and metastasis. In vitro experiment demonstrated that the interaction inhibited the phosphorylation of this protein by protein kinase C and protein kinase CK2. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Gene names

PPFIBP1, L2, hSGT2, hSgt2p, SGT2

Antibodie's label

unlabelled serum

Purity

Antibody is purified by protein A chromatography method.

Ab raised in

Rabbit

Type

Polyclonal

Antigen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PPFIBP1.

Immuno application

ELISA, Western Blot

Antibody advice

PPFIBP1 antibody can be used for detection of PPFIBP1 by ELISA at 1:312500. PPFIBP1 antibody can be used for detection of PPFIBP1 by western blot at 2.5 ug/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Suspention, pH, azide

Antibody is lyophilized in PBS buffer with 2% sucrose. Add 100 μL of distilled water. Final antibody concentration is 1 mg/mL.

Keep at

For short periods of storage (days) store at 4 grades C. For longer periods of storage, store PPFIBP1 antibody at -20 grades C. As with any antibody avoid repeat freeze-thaw cycles.

Works with

Human, Mouse, Rat

Omim nr

312032469

Ncbi nr

NP_803193

KDa

19 kDa, 113 kDa

Vial with antibody

Lyophilized

Quantity per ml

1 mg/ml

NCBI GENE nr

8496

GENE symbol

PPFIBP1

Antigene name

PTPRF interacting protein, binding protein 1 (liprin beta 1)

Source

Homo sapiens

Protein nr

Q86W92-5

Description

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.

Properties

If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

French translation

anticorps