Size

0.02 mg, 0.1 mg

Catalog No

7859

Price

180€

Buy: anti-PINK1 Antibody

Gene info

The PTEN-induced putative kinase 1 (PINK1) is a serine/threonine protein kinase that localizes to mitochondria and is thought to protect cells from stress-induced mitochondrial dysfunction (reviewed in 1). PINK1 recruits the E3 ubiquitin ligase Parkin to mitochondria to initiate mitophagy, an autophagic process that clears damaged mitochondria within a cell (2). PINK1 is cleaved by the mitochondrial protease PARL (3). Mutations in this gene cause one form of autosomal recessive early-onset Parkinson disease (4).

Gene names

PINK1 Antibody: BRPK, PARK6BRPK

Antibodie's label

unlabelled serum

Purity

PINK1 antibody is affinity chromatography purified via peptide column.

Ab raised in

Rabbit

Type

Polyclonal

Immunoglobulin

IgG

Spicific to

PINK1 antibody is human, mouse and rat reactive. At least two isoforms are known to exist; this antibody will only detect the longer isoform. PINK1 antibody will detect the cleaved and uncleaved form of PINK1.

Antigen

PINK1 antibody was made against a 16 amino acid peptide near the amino terminus of human PINK1.

Immuno application

ELISA, Western Blot

Antibody advice

PINK1 antibody can be used for detection of PINK1 by Western blot at 1 - 2 ug/ml.

Suspention, pH, azide

PINK1 antibody is supplied in PBS containing 0.02% sodium azide.

Keep at

PINK1 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year.

Works with

Human, Mouse, Rat

Omim nr

14165272

Ncbi nr

NP_115785

KDa

Predicted: 55 kDa Observed: 53 kDa

Vial with antibody

in solution

Quantity per ml

1 mg/mL

NCBI GENE nr

65018

GENE symbol

PINK1

Antigene name

PTEN induced putative kinase 1

Source

homo sapiens

Protein nr

Q9BXM7

Description

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.

Properties

If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

French translation

anticorps