PINK1 (C-terminal) - Blocking Peptide

Size

50 μg

Catalog No

X2775B

Price

168€

Buy: PINK1 (C-terminal) - Blocking Peptide

Category

Proteins & Peptides

Long description

This peptide is the immunogen used to make Cat # X2760P. _x000B__x000B_Protects against mitochondrial dysfunction during cellular stress, potentially by phosphorylating mitochondrial proteins. Involved in the clearance of damaged mitochondria via selective autophagy (mitophagy). It is necessary for PARK2 recruitment to dysfunctional mitochondria to initiate their degradation. Defects in PINK1 are the cause of Parkinson disease type 6 (PARK6). A neurodegenerative disorder characterized by parkinsonian signs such as rigidity, resting tremor and bradykinesia. A subset of patients manifest additional symptoms including hyperreflexia, autonomic instability, dementia and psychiatric disturbances. Symptoms show diurnal fluctuation and can improve after sleep.

Antibody come from

A fusion protein to the internal sequence GST

PINK1 (C-terminal) - Blocking Peptide

Other description

Provided as 0.2µm sterile filtered solution in phosphate buffered saline with 0.08% sodium azide.

Clone

not specified

Antigen-antibody binding interaction

PINK1 (C-terminal) - Blocking Peptide

PINK1 (C-terminal) - Blocking Peptide

Antibody is raised in

see techfile

Antibody's reacts with

Blocking Peptide to Cat # X2760P

Antibody's reacts with these species

This antibody doesn't cross react with other species

PINK1 (C-terminal) - Blocking Peptide

Antibody's specificity

No Data Available

Application

Blocking Peptide

Antibody's suited for

Application: Western Blots at 1:1000- 1:2,000_x000B_Optimal concentration should be evaluated by serial dilutions.

PINK1 (C-terminal) - Blocking Peptide

Storage

-20ºC

Relevant references

no information yet

Protein number

see ncbi

PINK1 (C-terminal) - Blocking Peptide

Warnings

This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.

Test

You can block the antibody by the specific target amino acid sequence of peptide.

Properties

blocking peptide

PINK1 (C-terminal) - Blocking Peptide

Description

Peptides short amino acid chains or epitopes or blocking antagonists. The shortest peptides are dipeptides, consisting of 2 amino acids joined by a single peptide bond, followed by tripeptides, tetra peptides, ... till polypeptides that are long, continuous, and unbranched synthetic peptide chains. These biological oligomers and polymers can be Solid-phase peptide synthesis (SPPS), or in continue produced for custom peptide synthesis projects. The High-efficiency solid phase peptide synthesis (HE-SPPS) is give very low production costs.

PINK1 (C-terminal) - Blocking Peptide