Proteins & Peptides
May regulate the disassembly of focal adhesions. May localize receptor-like tyrosine phosphatases type 2A at specific sites on the plasma membrane, possibly regulating their interaction with the extracellular environment and their association with substrates.
Rabbit polyclonal Caspase-5 antibody was raised against a 16 amino acid peptide from the amino-terminus of human Caspase-5.
Provided as solution in phosphate buffered saline with 0.02% sodium azide.
not specified
LAR/PTPRF - N Terminal GST Tag - Active Enzyme
E.coli
Human
This antibody doesn't cross react with other species
No Data Available
Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Caspase-5 (NT) antibody can be used for the detection of Caspase-5 by Western blot at 1 ug/ml. Depending on cell lines or tissues used, other cleavage products may be observed.
-20ºC
1. Martinon F and Tschopp J. Inflammatory caspases: linking an intracellular innate immune system to autoinflammatory diseases. Cell 2004; 117:561-74._x000B__x000B_2. Kuida K, Lippke JA, Ku G, et al. Altered cytokine export and apoptosis in mice deficient in interleukin-1 β converting enzyme. Science 1995; 267:2000-3._x000B__x000B_3. Gracie JA, Robertson SE, and McInnes IB. Interleukin-18. J. Leukoc. Biol. 2003; 73:213-224_x000B__x000B_4. Martinon F, Burns K, and Tschopp J. The inflammasome: a molecular platform triggering activation of the inflammatory caspases and processing of proIL-1_. Mol. Cell. 2002; 10:417-26.
see ncbi
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
Enzymes are cleaving the substrate. If the substrate is DNA they are called restriction enzymes. Activating enzymes will cut off the domain that is biological active to become functional.
