Target antigen
PTEN
Clonality
Polyclonal antibody
Clone
Polyclonal antibody
PTEN
Polyclonal antibody
Polyclonal antibody
rabbit
IgG polyclonal antibody
freeze-dried
human
WB
E.coli-derived human PTEN recombinant protein (Position: E91-V403). Human PTEN shares 99.7% amino acid (aa) sequence identity with mouse PTEN.
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Immunogen affinity purified.
The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
Keep the PTEN Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
The PTEN Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
PTEN is also known as BZS, DEC, CWS1, GLM2, MHAM, TEP1, PTEN1. It is mapped to 10q23.3. This gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded by this gene is a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates. The PTEN structure reveals a phosphatase domain that is similar to protein phosphatases but also has an enlarged active site important for the accommodation of the phosphoinositide substrate.
1. Lee, J.-O., Yang, H., Georgescu, M.-M., Di Cristofano, A., Maehama, T., Shi, Y., Dixon, J. E., Pandolfi, P., Pavletich, N. P. Crystal structure of the PTEN tumor suppressor: implications for its phosphoinositide phosphatase activity and membrane association. Cell 99: 323-334, 1999.
PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
phosphatase and tensin homolog
10q23del antibody|Bannayan Zonana syndrome antibody|BZS antibody|DEC antibody|GLM2 antibody|ITGA 2 antibody|MGC11227 antibody|MHAM antibody|MMAC 1 antibody|MMAC1 antibody|MMAC1 phosphatase and tensin homolog deleted on chromosome 10 antibody|Multiple hamartoma (Cowden syndrome) antibody|Mutated in multiple advanced cancers 1 antibody|Mutated in Mutiple Advanced Cancers 1 antibody|Phosphatase and Tensin Homolog antibody|Phosphatase and tensin like protein antibody|Phosphatidylinositol 345 trisphosphate 3 phosphatase and dual specificity protein phosphatase PTEN antibody|Phosphatidylinositol 345 trisphosphate 3 phosphatase antibody|Phosphatidylinositol-3,4,5-trisphosphate 3 phosphatase and dual-specificity protein phosphatase PTEN antibody|Platelet antigen BR antibody|PTEN 1 antibody|Pten antibody|PTEN_HUMAN antibody|PTEN1 antibody|Tensin homolog antibody|TEP 1 antibody|TEP1 antibody|VLA 2 Receptor Alpha Subunit antibody
P60484
5728
If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
anticorps
