Target antigen
Alkaline Phosphatase
Clonality
Polyclonal antibody
Clone
Polyclonal antibody
Alkaline Phosphatase
Polyclonal antibody
Polyclonal antibody
rabbit
IgG polyclonal antibody
freeze-dried
human, rat Predicted to work with: mouse
WB
A synthetic peptide corresponding to a sequence at the N-terminus of human Alkaline Phosphatase(31-45aa DQAQETLKYALELQK), different from the related mouse and rat sequences by three amino acids.
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Immunogen affinity purified.
The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
Keep the Alkaline Phosphatase Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
The Alkaline Phosphatase Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
Alkaline phosphatase(ALPL) removes phosphate groups from the 5' end of DNA and RNA, and from proteins, at high pH. Most mammals have 4 different isozymes: placental, placental like, intestinal and non tissue specific(found in liver, kidney and bone). Tissues with particularly high concentrations of ALP include the liver, bile ducts, placenta, and bone. ALPL is the alkaline phosphatase of skin fibroblasts,the tissue-nonspecific type, and that it is active toward millimolar concentrations of the putative natural substrates phosphoethanolamine(PEA) and pyridoxal-5-prime-phosphate(PLP). ALPL gene exists in single copy in the haploid genome and is composed of 12 exons distributed over more than 50 kb.Damaged or diseased tissue releases enzymes into the blood, so serum ALP measurements can be abnormal in many conditions, including bone disease and liver disease.
1. Fedde, K. N.; Whyte, M. P. : Alkaline phosphatase (tissue-nonspecific isoenzyme) is a phosphoethanolamine and pyridoxal-5-prime-phosphate ectophosphatase: normal and hypophosphatasia fibroblast study. Am. J. Hum. Genet. 47: 767-775, 1990. 2. Weiss, M. J.; Cole, D. E. C.; Ray, K.; Whyte, M. P.; Lafferty, M. A.; Mulivor, R. A.; Harris, H. : A missense mutation in the human liver/bone/kidney alkaline phosphatase gene causing a lethal form of hypophosphatasia. Proc. Nat. Acad. Sci. 85: 7666-7669, 1988.
ALPL
Alkaline phosphatase, tissue-nonspecific isozyme
alkaline phosphatase, liver/bone/kidney
Akp2 antibody|Alkaline phosphatase intestinal antibody|Alkaline phosphatase intestinal precursor antibody|Alkaline phosphatase liver/bone/kidney antibody|Alkaline phosphatase placental antibody|Alkaline phosphatase placental like 2 antibody|Alkaline phosphatase placental like antibody|Alkaline phosphatase placental type antibody|Alkaline phosphomonoesterase antibody|ALP 1 antibody|ALP antibody|ALP I antibody|ALP L antibody|ALP P antibody|ALPG antibody|ALPI antibody|ALPL antibody|ALPP antibody|ALPPL antibody|ALPPL2 antibody|AP TNAP antibody|FLJ40094 antibody|GCAP antibody|Germ cell alkaline phosphatase antibody|Glycerophosphatase antibody|HOPS antibody|IAP antibody|Intestinal alkaline phosphatase antibody|Kasahara isozyme antibody|Nagao isozyme antibody|OTTHUMP00000164357 antibody|Placental alkaline phosphatase antibody|Placental like alkaline phosphatase antibody|PLAP 1 antibody|PLAP antibody|PLAP like antibody|Regan isozyme antibody|Testicular and thymus alkaline phosphatase antibody|Tissue non specific alkaline phosphatase antibody|Tissue nonspecific ALP antibody|TNAP antibody|TNSALP antibody
P05186
If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
anticorps
