Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
liquid
Immunogen affinity purified
≥95% as determined by SDS-PAGE
PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
This gene encodes a cytoskeletal protein that is highly expressed in hemopoietic tissues. This protein functions via its interaction with several different proteins involved in cytoskeletal organization and inflammatory processes. It binds to the cytoplasmic tail of CD2, an effector of T cell activation and adhesion, downregulating CD2-triggered adhesion. It binds PEST-type protein tyrosine phosphatases (PTP) and directs them to c-Abl kinase to mediate c-Abl dephosphorylation, thereby, regulating c-Abl activity. It also interacts with pyrin, which is found in association with the cytoskeleton in myeloid/monocytic cells and modulates immunoregulatory functions. Mutations in this gene are associated with PAPA (pyogenic sterile arthritis, pyoderma gangrenosum, and acne) syndrome. It is hypothesized that the disease-causing mutations compromise physiologic signaling necessary for the maintenance of a proper inflammatory response.
proline-serine-threonine phosphatase interacting protein 1
CD2BP1
48 kDa
O43586
Human, Mouse, Rat
ELISA, WB, IHC
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Immunohistochemistry of paraffin-embedded human brain using FNab06903(PSTPIP1 antibody) at dilution of 1:50
mouse thymus tissue were subjected to SDS PAGE followed by western blot with FNab06903(PSTPIP1 antibody) at dilution of 1:1000
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.Antibody for research use.
If you buy Antibodies supplied by FineTest they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
anticorps
