Immunogen
Synthesized peptide derived from C-terminal of human SLC6A8.
Antibody's target
Human SLC6A8
Antibody's full description
Rabbit Anti-Human SLC6A8 Polyclonal
100 µl
SPC-1333D-ALP
350€
Synthesized peptide derived from C-terminal of human SLC6A8.
Human SLC6A8
Rabbit Anti-Human SLC6A8 Polyclonal
Cell Signaling
Polyclonal Antibodies
SLC6A 8 Antibody, Creatine transporter 1 Antibody, CRTR Antibody, CT1 Antibody, Sodium and chloride-dependent creatine transporter 1 Antibody, Solute carrier family 6 member 8 Antibody
WB, ELISA
Rabbit
Human, Mouse, Rat
WB (1:1000), ELISA (1:10000); optimal dilutions for assays should be determined by the user.
Peptide Affinity Purified
PBS pH 7.4, 50% glycerol, 150mM NaCl, 0.02% sodium azide
See included datasheet or contact our support service
Detects ~70kDa, endogenous levels of total SLC6A8 protein.
-20°C
Blue Ice or 4°C
A 1:1000 dilution of SPC-1333 was sufficient for detection of SLC6A8 in 10 µg of HuvEc cell lysates by ECL immunoblot analysis using Goat Anti-Rabbit IgG:HRP as the secondary antibody.
Membrane
Predominantly expressed in skeletal muscle and kidney. Also found in brain, heart, colon, testis and prostate.
SLC6A8 is required for the uptake of creatine in muscles and brain. Deficiency of this gene is an X-linked form of intellectual diavility and is the most common casue of cerebral creatine syndromes.
6/Sep/2016
NP_005620.1
6535
P48029
Refer to PubMed
To be tested
To be tested
Contact our support service to receive datasheet or other technical documentation.
Western blot analysis of Human HuvEc cell lysates showing detection of ~70kDa SLC6A8 protein using Rabbit Anti-SLC6A8 Polyclonal Antibody (SPC-1333). Lane 1: Human HUVEC cells. Lane 2: Human HUVEC cells treated with the immunizing peptide. Primary Antibody: Rabbit Anti-SLC6A8 Polyclonal Antibody (SPC-1333) at 1:1000. Predicted/Observed Size: ~70kDa. Rabbit Anti-SLC6A8 Antibody used in Western blot (WB) on HuvEc cell lysates (SPC-1333)
Non-hazardous
Canada
1.4
0.1
In Stock
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
StressMark antibodies supplies antibodies that are for research of human proteins.
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Polyclonals and antibodies
Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.Rabbits are used for polyclonal antibody production by StressMark antibodies. Rabbit antibodies are very stable and can be stored for several days at room temperature. StressMark antibodies adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
Oryctolagus cuniculus
