Immunogen
A synthesized peptide derived from human FOXP3
Antibody's target
Human FOXP3
Antibody's full description
Rabbit Anti-Human FOXP3 Polyclonal
100 µl
SPC-1323D-ALP
350€
A synthesized peptide derived from human FOXP3
Human FOXP3
Rabbit Anti-Human FOXP3 Polyclonal
Polyclonal Antibodies
AIID antibody, DIETER antibody, Forkhead box P3 antibody, Forkhead box protein P3 antibody, FOXP3 antibody, FOXP3_HUMAN antibody, FOXP3delta7 antibody, Immune dysregulation polyendocrinopathy enteropathy X linked antibody, Immunodeficiency polyendocrinopathy enteropathy X linked antibody, IPEX antibody, JM2 antibody, MGC141961 antibody, MGC141963 antibody, OTTHUMP00000025832 antibody, OTTHUMP00000025833 antibody, OTTHUMP00000226737 antibody, PIDX antibody, Scurfin antibody, XPID antibody
WB, IHC, ICC/IF, IP
Rabbit
Human
WB (1:2000), IHC (1:200), ICC/IF (1:500); optimal dilutions for assays should be determined by the user.
Peptide Affinity Purified
PBS pH 7.4, 50% glycerol, 150mM NaCl, 0.02% sodium azide
See included datasheet or contact our support service
Detects endogenous levels of total FOXP3
-20°C
Blue Ice or 4°C
A 1:1000 dilution of SPC-1323 was sufficient for detection of FOXP3 in 10 µg of Jurkat cell lysates by ECL immunoblot analysis using Goat Anti-Rabbit IgG:HRP as the secondary antibody.
Nucleus, Cytoplasm
See included datasheet or contact our support service.
FOXP3 (forkhead box P3), also known as scurfin, is a protein involved in immune system responses. A member of the FOX protein family, FOXP3 appears to function as a master regulator of the regulatory pathway in the development and function of regulatory T cells. FOXP3 is stably and constitutively expressed at a high level in CD25 + CD4 positive regulatory T cells, a low level in CD4-positive/CD25-negative cells, and is absent in CD4-negative/CD8-positive T cells. FOXP3 may be a master regulatory gene and a more specific marker of regulatory T cells than other T cells.
1. Brunkow ME. et al. (2001) Nature Genetics 27 (1): 68–73. 2. Hori S. et al. (2003) Science 299 (5609): 1057–61. 3. Fontenot JD. et al. (2003) Nature Immunology 4 (4): 330–6. 4. Fontenot JD. et al. (2005) Immunity 22 (3): 329–41.
6/Sep/2016
NP_054728.2
50943
Q9BZS1
Refer to PubMed
To be tested
To be tested
Contact our support service to receive datasheet or other technical documentation.
No Data Available
Non-hazardous
Canada
1.4
0.1
In Stock
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
StressMark antibodies supplies antibodies that are for research of human proteins.
Forkhead Box Protein P3 scurfin FOXP3, is a protein involved in immune system responses. A member of the FOX protein family, FOXP3 appears to function as a master regulator of the regulatory pathway in the development and function of regulatory T cells. Foxp3 or forkhead box P3 or skurfin or scurfin or skurfina is also known as IPEX, AIID, PIDX, XPID and DIETER.
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Polyclonals and antibodies
Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.Rabbits are used for polyclonal antibody production by StressMark antibodies. Rabbit antibodies are very stable and can be stored for several days at room temperature. StressMark antibodies adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
Oryctolagus cuniculus
