Rabbit Anti-Human YSK4 Polyclonal: Alkaline Phosphatase

Size

100 µl

Catalog No

SPC-1217D-ALP

Price

391€

Immunogen

Synthetic peptide of human YSK4 (AA350-366)

Antibody's target

Human YSK4

Antibody's full description

Rabbit Anti-Human YSK4 Polyclonal

Rabbit Anti-Human YSK4 Polyclonal: Alkaline Phosphatase

Antibody's category

Polyclonal Antibodies

Antibody's other name

EC 2.7.11 Antibody, RCK Antibody, regulated in COPD kinase Antibody, SPS1/STE20-related protein kinase YSK4 Antibody, Yeast Sps1/Ste20-related kinase 4 (S. cerevisiae) Antibody, yeast Sps1/Ste20-related kinase 4 Antibody, YSK4 Sps1/Ste20-related kinase homolog (S. cerevisiae) Antibody

Verified applications

WB, AM

Rabbit Anti-Human YSK4 Polyclonal: Alkaline Phosphatase

Raised in

Rabbit

Antibody's reactivity

Human, Mouse

Antibody's recommended dilutions for use

WB (1:250); optimal dilutions for assays should be determined by the user.

Rabbit Anti-Human YSK4 Polyclonal: Alkaline Phosphatase

Antibody's purified from

Peptide Affinity Purified

Recommended buffer for storage

PBS pH7.4, 50% glycerol, 0.025% Thimerosal

Antibody's concentration

See included datasheet or contact our support service

Rabbit Anti-Human YSK4 Polyclonal: Alkaline Phosphatase

Antibody's specificity

Detects 150.54 kDa.

Storage recommendations

-20°C

Shipping recommendations

Blue Ice or 4°C

Rabbit Anti-Human YSK4 Polyclonal: Alkaline Phosphatase

Certificate of analysis

A 1:250 dilution of SPC-1217 was sufficient for detection of YSK4 in 10 µg of HeLa cell lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.

Antibody in cell

Cytoplasm

Tissue specificity

See included datasheet or contact our support service.

Rabbit Anti-Human YSK4 Polyclonal: Alkaline Phosphatase

Scientific context

YSK4 (YSK4 Sps1/Ste20-related kinase homolog (S. cerevisiae)), also known as RCK (regulated in COPD, protein kinase), is a 1,328 amino acid protein that belongs to the STE Ser/Thr protein kinase family, STE20 subfamily and protein kinase superfamily. Containing one protein kinase domain, YSK4 exists as six alternatively spliced isoforms that are encoded by a gene that maps to human chromosome 2 and mouse chromosome 1. Human chromosome 2 consists of 237 million bases, encodes over 1,400 genes and makes up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alström syndrome, is due to mutations in the ALMS1 gene.

Bibliography

Refer to PubMed

Released date

29/Aug/2016

Rabbit Anti-Human YSK4 Polyclonal: Alkaline Phosphatase

NCBI number

NP_079328

Gene number

80122

Protein number

Q56UN5

Rabbit Anti-Human YSK4 Polyclonal: Alkaline Phosphatase

PubMed number

Refer to PubMed

Tested applications

To be tested

Tested reactivity

To be tested

Rabbit Anti-Human YSK4 Polyclonal: Alkaline Phosphatase

Antibody's datasheet

Contact our support service to receive datasheet or other technical documentation.

Representative figure link

No Data Available

Warning information

Non-hazardous

Rabbit Anti-Human YSK4 Polyclonal: Alkaline Phosphatase

Country of production

Canada

Total weight (kg)

1.4

Net weight (g)

0.1

Rabbit Anti-Human YSK4 Polyclonal: Alkaline Phosphatase

Stock availabilit

In Stock

Description

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.

Test

StressMark antibodies supplies antibodies that are for research of human proteins.

Rabbit Anti-Human YSK4 Polyclonal: Alkaline Phosphatase

Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

Group

Polyclonals and antibodies

About

Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.Rabbits are used for polyclonal antibody production by StressMark antibodies. Rabbit antibodies are very stable and can be stored for several days at room temperature. StressMark antibodies adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.

Rabbit Anti-Human YSK4 Polyclonal: Alkaline Phosphatase

Latin name

Oryctolagus cuniculus

Rabbit Anti-Human YSK4 Polyclonal: Alkaline Phosphatase