Immunogen
Synthetic peptide of human ROS (AA1924-1938)
Antibody's target
Human ROS
Antibody's full description
Rabbit Anti-Human ROS Polyclonal
100 µl
SPC-1198D-ALP
391€
Synthetic peptide of human ROS (AA1924-1938)
Human ROS
Rabbit Anti-Human ROS Polyclonal
Polyclonal Antibodies
c ros antibody, c ros oncogene 1 receptor tyrosine kinase antibody, c ros1 antibody, MCF 3 antibody, MCF3 antibody, Proto oncogene c ros 1 protein antibody, Proto oncogene c Ros antibody, Ros 1 antibody, ROS 1C antibody, ROS antibody, ROS_HUMAN antibody, ROS1 antibody, ROS1C antibody, Transmembrane tyrosine specific protein kinase antibody, v ros avian UR2 sarcoma virus oncogene homolog 1 antibody, v ros UR2 sarcoma virus oncogene homolog 1 antibody
WB, AM
Rabbit
Human
WB (1:250); optimal dilutions for assays should be determined by the user.
Peptide Affinity Purified
PBS pH7.4, 50% glycerol, 0.025% Thimerosal
See included datasheet or contact our support service
Detects 263.915 kDa.
-20°C
Blue Ice or 4°C
A 1:250 dilution of SPC-1198 was sufficient for detection of ROS in 10 µg of 293T cell lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
Membrane
Expressed in brain. Expression is increased in primary gliomas.
ROS1 is a receptor-tyrosine kinase that is activated upon binding an unidentified ligand. It has been suggested to activate several downstream signalling pathways in cell differentiation, proliferation, growth and survival including the PI3 kinase-mTOR signalling pathway. Ros1 is highly expressed in several human cancers. However, its pattern of diverse mutations in human tumours is characteristic of a tumour suppressor protein.
Refer to PubMed
29/Aug/2016
NP_002935
6098
P08922
Refer to PubMed
To be tested
To be tested
Contact our support service to receive datasheet or other technical documentation.
No Data Available
Non-hazardous
Canada
1.4
0.1
In Stock
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
StressMark antibodies supplies antibodies that are for research of human proteins.
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Polyclonals and antibodies
Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.Rabbits are used for polyclonal antibody production by StressMark antibodies. Rabbit antibodies are very stable and can be stored for several days at room temperature. StressMark antibodies adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
Oryctolagus cuniculus