Immunogen
Synthetic peptide of human MAPK12 (AA323-337)
Antibody's target
Human MAPK12
Antibody's full description
Rabbit Anti-Human MAPK12 Polyclonal
100 µl
SPC-1182D-ALP
391€
Synthetic peptide of human MAPK12 (AA323-337)
Human MAPK12
Rabbit Anti-Human MAPK12 Polyclonal
Polyclonal Antibodies
ERK 3 antibody, ERK 5 antibody, ERK 6 antibody, Extracellular signal-regulated kinase 6 antibody, MAP kinase 12 antibody, MAP kinase p38 gamma antibody, MAPK 12 antibody, Mapk12 antibody, Mitogen Activated Protein Kinase 12 antibody, Mitogen activated protein kinase 3 antibody, Mitogen activated protein kinase p38 gamma antibody, Mitogen-activated protein kinase 12 antibody, Mitogen-activated protein kinase p38 gamma antibody, MK12_HUMAN antibody, P38GAMMA antibody, PRKM12 antibody, SAPK3 antibody, Stress Activated Protein Kinase 3 antibody
WB, AM
Rabbit
Human, Mouse
WB (1:250); optimal dilutions for assays should be determined by the user.
Peptide Affinity Purified
PBS pH7.4, 50% glycerol, 0.025% Thimerosal
See included datasheet or contact our support service
Detects 41.94 kDa.
-20°C
Blue Ice or 4°C
A 1:250 dilution of SPC-1182 was sufficient for detection of MAPK12 in 10 µg of HeLa cell lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
Cytoplasm, Mitochondrion
Highly expressed in skeletal muscle and heart.
MAPK12 is a protein-serine/threonine kinase. Part of the p38 stress pathway which prevents cell cycle progression. Many cancer cells will upregulate MAPK12 activity to kill cancer cells. Loss of function may be important to confer survival and inhibit apoptosis for tumour cells.
Refer to PubMed
29/Aug/2016
NP_002960
6300
P53778
Refer to PubMed
To be tested
To be tested
Contact our support service to receive datasheet or other technical documentation.
No Data Available
Non-hazardous
Canada
1.4
0.1
In Stock
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
StressMark antibodies supplies antibodies that are for research of human proteins.
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Polyclonals and antibodies
Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.Rabbits are used for polyclonal antibody production by StressMark antibodies. Rabbit antibodies are very stable and can be stored for several days at room temperature. StressMark antibodies adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
Oryctolagus cuniculus