Immunogen
Synthetic peptide of human MEK4 (AA323-337)
Antibody's target
Human MEK4
Antibody's full description
Rabbit Anti-Human MEK4 Polyclonal
100 µl
SPC-1170D-ALP
391€
Synthetic peptide of human MEK4 (AA323-337)
Human MEK4
Rabbit Anti-Human MEK4 Polyclonal
Polyclonal Antibodies
C-JUN N-terminal kinase kinase 1 antibody, Dual specificity mitogen activated protein kinase kinase 4 antibody, Dual specificity mitogen-activated protein kinase kinase 4 antibody, JNK Activated Kinase 1 antibody, JNKK antibody, JNKK1 antibody, MAP kinase kinase 4 antibody, Map2k4 antibody, MAPK ERK kinase 4 antibody, MAPK/ERK kinase 4 antibody, MAPKK 4 antibody, MEK 4 antibody, MEK4 antibody, Mitogen activated protein kinase kinase 4 antibody, MKK4 antibody, MP2K4_HUMAN antibody, PRKMK4 antibody, SAPK ERK kinase 1 antibody, SAPKK 1 antibody, SEK1 antibody, SERK1 antibody, SKK1 antibody, Stress activated protein kinase kinase 1 antibody
WB, AM
Rabbit
Human, Mouse
WB (1:250); optimal dilutions for assays should be determined by the user.
Peptide Affinity Purified
PBS pH7.4, 50% glycerol, 0.025% Thimerosal
See included datasheet or contact our support service
Detects 44kDa.
-20°C
Blue Ice or 4°C
A 1:250 dilution of SPC-1170 was sufficient for detection of MEK4 in 10 µg of HeLa cell lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
Cytoplasm, Nucleus
Abundant expression is seen in the skeletal muscle. It is also widely expressed in other tissues.
MAP2K4 is a protein-serine/threonine/tyrosine kinase. Involved in MAPK signalling in response to stressors or mitogens. It signals through JNK1/JNK2, ERK1/ERK2, p38 and more. It has arole in maintaining peripheral lymphoid homeostasis and apoptosis. Mutations and deletions of this genes leads to dysregulated JNK signalling and promotes oncogenesis.
Refer to PubMed
29/Aug/2016
NP_003001
6416
P45985
Refer to PubMed
To be tested
To be tested
Contact our support service to receive datasheet or other technical documentation.
No Data Available
Non-hazardous
Canada
1.4
0.1
In Stock
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
StressMark antibodies supplies antibodies that are for research of human proteins.
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Polyclonals and antibodies
Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.Rabbits are used for polyclonal antibody production by StressMark antibodies. Rabbit antibodies are very stable and can be stored for several days at room temperature. StressMark antibodies adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
Oryctolagus cuniculus