Immunogen
Synthetic peptide of human JAK2 (AA1118-1132)
Antibody's target
Human JAK2
Antibody's full description
Rabbit Anti-Human JAK2 Polyclonal
100 µl
SPC-1149D-ALP
391€
Synthetic peptide of human JAK2 (AA1118-1132)
Human JAK2
Rabbit Anti-Human JAK2 Polyclonal
Polyclonal Antibodies
JAK 2 Antibody, JAK-2 Antibody, JAK2_HUMAN Antibody, Janus Activating Kinase 2 Antibody, JTK 10 Antibody, kinase Jak2 Antibody, THCYT3 Antibody, Tyrosine protein kinase JAK2 Antibody
WB, AM
Rabbit
Human, Mouse
WB (1:250); optimal dilutions for assays should be determined by the user.
Peptide Affinity Purified
PBS pH7.4, 50% glycerol, 0.025% Thimerosal
See included datasheet or contact our support service
Detects 130.674 kDa.
-20°C
Blue Ice or 4°C
A 1:250 dilution of SPC-1149 was sufficient for detection of JAK2 in 10 µg of HeLa cell lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
Endomembrane system, Nucleus
Expressed in blood, bone marrow and lymph node.
JAK2 is a non-receptor protein-tyrosine kinase. Involved in cellular responses to growth factors and cytokines such as IL-3, GM-CSF and erythropoietin. Phosphorylates specific tyrosine residues on the cytoplasmic tails of the receptor, creating docking sites for STATs proteins. Subsequently, phosphorylates receptor bound STATs, which then form homo- or heterodimers and migrate to the nucleus to activate gene transcription.
Refer to PubMed
29/Aug/2016
NP_004963
3717
O60674
Refer to PubMed
To be tested
To be tested
Contact our support service to receive datasheet or other technical documentation.
No Data Available
Non-hazardous
Canada
1.4
0.1
In Stock
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
StressMark antibodies supplies antibodies that are for research of human proteins.
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Polyclonals and antibodies
Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.Rabbits are used for polyclonal antibody production by StressMark antibodies. Rabbit antibodies are very stable and can be stored for several days at room temperature. StressMark antibodies adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
Oryctolagus cuniculus