Immunogen
A synthetic peptide of human DUSP6 (AA 76-90)
Antibody's target
Human DUSP6
Antibody's full description
Rabbit Anti-Human DUSP6 Polyclonal
100 µl
SPC-1127D-ALP
391€
A synthetic peptide of human DUSP6 (AA 76-90)
Human DUSP6
Rabbit Anti-Human DUSP6 Polyclonal
Polyclonal Antibodies
Dual specificity phosphatase 6 antibody, Dual specificity phosphatase 6 isoform a antibody, Dual specificity protein phosphatase 6 antibody, Dual specificity protein phosphatase PYST1 antibody, DUS6_HUMAN antibody, DUSP 6 antibody, DUSP 6a antibody, Dusp6 antibody, DUSP6a antibody, HH19 antibody, MAP kinase phosphatase 3 antibody, Mitogen activated protein kinase phosphatase 3 antibody, Mitogen-activated protein kinase phosphatase 3 antibody, MKP 3 antibody, PYST 1 antibody, PYST1 antibody, Serine/threonine specific protein phosphatase antibody
WB, AM
Rabbit
Human, Mouse
WB (1:250); optimal dilutions for assays should be determined by the user.
Peptide Affinity Purified
PBS pH7.4, 50% glycerol, 0.025% Thimerosal
See included datasheet or contact our support service
Detects 42.32 kDa.
-20°C
Blue Ice or 4°C
A 1:250 dilution of SPC-1127 was sufficient for detection of DUSP6 in 10 µg of HeLa cell lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
Cytoplasm
See included datasheet or contact our support service.
DUSP6 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli.
Refer to PubMed
29/Aug/2016
NP_001937
1848
Q16828
Refer to PubMed
To be tested
To be tested
Contact our support service to receive datasheet or other technical documentation.
No Data Available
Non-hazardous
Canada
1.4
0.1
In Stock
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
StressMark antibodies supplies antibodies that are for research of human proteins.
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Polyclonals and antibodies
Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.Rabbits are used for polyclonal antibody production by StressMark antibodies. Rabbit antibodies are very stable and can be stored for several days at room temperature. StressMark antibodies adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
Oryctolagus cuniculus