Immunogen
Synthetic peptide of human Akt2 (AA454-468)
Antibody's target
Human AKT2
Antibody's full description
Rabbit Anti-Human AKT2 Polyclonal
100 µl
SPC-1101D-ALP
391€
Synthetic peptide of human Akt2 (AA454-468)
Human AKT2
Rabbit Anti-Human AKT2 Polyclonal
Polyclonal Antibodies
Akt2 antibody, AKT2_HUMAN antibody, HIHGHH antibody, PKB antibody, PKB beta antibody, PKBB antibody, PKBBETA antibody, Protein kinase Akt 2 antibody, Protein kinase B beta antibody, RAC-BETA antibody, RAC-beta serine/threonine-protein kinase antibody, RAC-PK-beta antibody, v akt murine thymoma viral oncogene homolog 2 antibody
WB, AM
Rabbit
Human, Mouse
WB (1:250); optimal dilutions for assays should be determined by the user.
Peptide Affinity Purified
PBS pH7.4, 50% glycerol, 0.025% Thimerosal
See included datasheet or contact our support service
Detects 55.769 kDa.
-20°C
Blue Ice or 4°C
A 1:250 dilution of SPC-1101 was sufficient for detection of AKT2 in 10 µg of HEK293 cell lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
Cytoplasm, Nucleus, Cell Membrane
Expressed in all human cell types so far analyzed.
AKT2 is a protein-serine/threonine kinase. It is closely related to AKT1 and AKT3. Its cell signalling activities involve activating cell surival and proliferation, increasing metabolism, and angiogenesis. Its interaction network contains over 100 substrates which includes inhibiting p53 via downstream signalling, activating mTOR, inhibition of GSK3B, and inhibition of cyclins. In cancer, it is found to be overexpressed and amplified. It is also linked with invasion, cell migration and induction of angiogenesis.
Refer to PubMed
29/Aug/2016
NP_001617
208
P31751
Refer to PubMed
To be tested
To be tested
Contact our support service to receive datasheet or other technical documentation.
No Data Available
Non-hazardous
Canada
1.4
0.1
In Stock
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
StressMark antibodies supplies antibodies that are for research of human proteins.
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Polyclonals and antibodies
Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.Rabbits are used for polyclonal antibody production by StressMark antibodies. Rabbit antibodies are very stable and can be stored for several days at room temperature. StressMark antibodies adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
Oryctolagus cuniculus