Immunogen
A phospho-specific peptide corresponding to residues surrounding Ser382 of human WNK1 (AA379-385)
Antibody's target
Human WNK1 (pSer382)
Antibody's full description
Rabbit Anti-Human WNK1 (pSer382) Polyclonal
100 µl
SPC-1097D-ALP
391€
A phospho-specific peptide corresponding to residues surrounding Ser382 of human WNK1 (AA379-385)
Human WNK1 (pSer382)
Rabbit Anti-Human WNK1 (pSer382) Polyclonal
Polyclonal Antibodies
Erythrocyte 65 kDa protein Antibody, HSAN2 Antibody, HSN2 Antibody, hWNK1 Antibody, KDP Antibody, KIAA0344 Antibody, Kinase deficient protein Antibody, MGC163339 Antibody, MGC163341 Antibody, p65 Antibody, PRKWNK1 Antibody, Prostate derived sterile 20 like kinase Antibody, Protein kinase lysine deficient 1 Antibody, Protein kinase lysine-deficient 1 Antibody, Protein kinase with no lysine 1 Antibody, PSK Antibody, Serine/threonine protein kinase WNK1 Antibody, Serine/threonine-protein kinase WNK1 Antibody, With no K Antibody, WNK lysine deficient protein kinase 1 Antibody, WNK1 Antibody, WNK1_HUMAN Antibody
WB, AM
Rabbit
Human
WB (1:250); optimal dilutions for assays should be determined by the user.
Peptide Affinity Purified
PBS pH7.4, 50% glycerol, 0.025% Thimerosal
See included datasheet or contact our support service
Detects 250.756 kDa.
-20°C
Blue Ice or 4°C
A 1:250 dilution of SPC-1097 was sufficient for detection of WNK1 (pSer382) in 10 µg of HeLa cell lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
Cytoplasm
Highly expressed in the testis, heart, kidney and skeletal muscle. Isoform 3 is kidney-specific and specifically expressed in the distal convoluted tubule (DCT) and connecting tubule (CNT) of the nephron.
WINK1 is a serine/threonine kinase which plays an important role in the regulation of electrolyte homeostasis, cell signalling, survival, and proliferation.WNK1 activates SCNN1A, SCNN1B, SCNN1D and SGK1. Exact mechanism of oncogenesis is unclear.
Refer to PubMed
29/Aug/2016
NP_061852
65125
Q9H4A3
Refer to PubMed
To be tested
To be tested
Contact our support service to receive datasheet or other technical documentation.
No Data Available
Non-hazardous
Canada
1.4
0.1
In Stock
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
StressMark antibodies supplies antibodies that are for research of human proteins.
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Polyclonals and antibodies
Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.Rabbits are used for polyclonal antibody production by StressMark antibodies. Rabbit antibodies are very stable and can be stored for several days at room temperature. StressMark antibodies adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
Oryctolagus cuniculus