Immunogen
A phospho-specific peptide corresponding to residues surrounding Tyr681 of human Tyro3 (AA678-684)
Antibody's target
Human TYRO3 (pTyr681)
Antibody's full description
Rabbit Anti-Human TYRO3 (pTyr681) Polyclonal
100 µl
SPC-1092D-ALP
391€
A phospho-specific peptide corresponding to residues surrounding Tyr681 of human Tyro3 (AA678-684)
Human TYRO3 (pTyr681)
Rabbit Anti-Human TYRO3 (pTyr681) Polyclonal
Polyclonal Antibodies
Brt Antibody, BYK Antibody, DTK Antibody, RSE Antibody, SKY Antibody, Tif Antibody, tyro3 Antibody, TYRO3_HUMAN Antibody, Tyrosine-protein kinase byk Antibody, Tyrosine-protein kinase DTK Antibody, Tyrosine-protein kinase receptor TYRO3 Antibody, Tyrosine-protein kinase RSE Antibody, Tyrosine-protein kinase SKY Antibody
WB, AM
Rabbit
Human
WB (1:250); optimal dilutions for assays should be determined by the user.
Peptide Affinity Purified
PBS pH7.4, 50% glycerol, 0.025% Thimerosal
See included datasheet or contact our support service
Detects 96.905 kDa.
-20°C
Blue Ice or 4°C
A 1:250 dilution of SPC-1092 was sufficient for detection of TYRO3 (pTyr681) in 10 µg of mouse brain lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
Cell membrane
Highly expressed in the brain. Lower levels in other tissues.
TYRO3 responds to TUB, TULP1, GAS6 and protein S as ligands and regulates cell survival, proliferation, immunoregulation, phagocytosis, cell migration, actin organization, spermatogenesis, platelet aggregation, clot stabilization, memory formation, circadian rhythm and synaptic plasticity. signalling transduction can occur via MAPK/ERK and Pi3K/AKT pathways. Overexpression by various cancers provide transformative ability and increased survival signals.
Refer to PubMed
29/Aug/2016
NP_006284
7301
Q06418
Refer to PubMed
To be tested
To be tested
Contact our support service to receive datasheet or other technical documentation.
No Data Available
Non-hazardous
Canada
1.4
0.1
In Stock
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
StressMark antibodies supplies antibodies that are for research of human proteins.
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Polyclonals and antibodies
Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.Rabbits are used for polyclonal antibody production by StressMark antibodies. Rabbit antibodies are very stable and can be stored for several days at room temperature. StressMark antibodies adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
Oryctolagus cuniculus