Immunogen
A phospho-specific peptide corresponding to residues surrounding Tyr323 of human Syk (AA320-326)
Antibody's target
Human Syk (pTyr323)
Antibody's full description
Rabbit Anti-Human Syk (pTyr323) Polyclonal
100 µl
SPC-1085D-ALP
391€
A phospho-specific peptide corresponding to residues surrounding Tyr323 of human Syk (AA320-326)
Human Syk (pTyr323)
Rabbit Anti-Human Syk (pTyr323) Polyclonal
Polyclonal Antibodies
p72-Syk Antibody, p72syk Antibody, Spleen tyrosine kinase Antibody, Syk Antibody, Tyrosine protein kinase SYK Antibody, Tyrosine-protein kinase SYK Antibody, EC 2.7.10.2 Antibody, kinase Syk Antibody, KSYK Antibody, KSYK_HUMAN Antibody
WB, AM
Rabbit
Human
WB (1:250); optimal dilutions for assays should be determined by the user.
Peptide Affinity Purified
PBS pH7.4, 50% glycerol, 0.025% Thimerosal
See included datasheet or contact our support service
Detects 72.066 kDa.
-20°C
Blue Ice or 4°C
A 1:250 dilution of SPC-1085 was sufficient for detection of Syk (pTyr323) in 10 µg of mouse spleen lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
Cell Membrane, Cytoplasm
Highly expressed in hematopoietic cells (at protein level). Within the B-cells compartment it is expressed in pro-B-cells to plasma cells.
Syk is involved in BCR signal transduction. It can signal through PI3K or PLC depending on cell context and phoshrorylation state. SYK exprssion is lost in breast cancer and facilitate tumour growth and metastasis. A tranlocation with ETV6 mediates an overactive protein and dysregulated signal
Refer to PubMed
29/Aug/2016
NP_003168
6850
P43405
Refer to PubMed
To be tested
To be tested
Contact our support service to receive datasheet or other technical documentation.
No Data Available
Non-hazardous
Canada
1.4
0.1
In Stock
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
StressMark antibodies supplies antibodies that are for research of human proteins.
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Polyclonals and antibodies
Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.Rabbits are used for polyclonal antibody production by StressMark antibodies. Rabbit antibodies are very stable and can be stored for several days at room temperature. StressMark antibodies adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
Oryctolagus cuniculus