Immunogen
A phospho-specific peptide corresponding to residues surrounding Thr182 of human SIK1 (AA179-185)
Antibody's target
Human SIK1 (pThr182)
Antibody's full description
Rabbit Anti-Human SIK1 (pThr182) Polyclonal
100 µl
SPC-1082D-ALP
391€
A phospho-specific peptide corresponding to residues surrounding Thr182 of human SIK1 (AA179-185)
Human SIK1 (pThr182)
Rabbit Anti-Human SIK1 (pThr182) Polyclonal
Polyclonal Antibodies
SNF1LK Antibody, KID2 Antibody, MSK Antibody, myocardial SNF1 like kinase Antibody, QIK Antibody, Qin-induced kinase Antibody, Salt inducible kinase 1 Antibody, Salt-inducible protein kinase 1 Antibody, Serine threonine protein kinase SNF1 like kinase 1 Antibody, Serine threonine protein kinase SNF1LK Antibody, Serine/threonine-protein kinase SIK1 Antibody, Serine/threonine-protein kinase SNF1-like kinase 1 Antibody, Serine/threonine-protein kinase SNF1LK Antibody, SIK-1 Antibody, SIK1 Antibody, SIK1_HUMAN Antibody, SNF1 like kinase Antibody
WB, AM
Rabbit
Human
WB (1:250); optimal dilutions for assays should be determined by the user.
Peptide Affinity Purified
PBS pH7.4, 50% glycerol, 0.025% Thimerosal
See included datasheet or contact our support service
Detects 84.902 kDa.
-20°C
Blue Ice or 4°C
A 1:250 dilution of SPC-1082 was sufficient for detection of SIK1 (pThr182) in 10 µg of 293T cell lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
Cytoplasm, Nucleus
Highly expressed in the cornea, keratinocytes, and B-lympocytes. Lower expression found in many organs.
SIK1 (salt-inducible kinase 1), also known as SNF1LK or MSK, is a 783 amino acid protein that contains one UBA domain and one protein kinase domain and belongs to the Ser/Thr protein kinase family. Localized to both the nucleus and the cytoplasm, SIK1 uses magnesium as a cofactor to catalyze the ATP-dependent phosphorylation of target proteins and is thought to be important for the early stages of skeletal muscle growth and myocardial cell differentiation. Additionally, SIK1 has a potential role in regulation of the G2/M cell cycle transition, as well as in inhibitory control of CREB protein function.
Refer to PubMed
29/Aug/2016
NP_775490
102724428
P57059
Refer to PubMed
To be tested
To be tested
Contact our support service to receive datasheet or other technical documentation.
No Data Available
Non-hazardous
Canada
1.4
0.1
In Stock
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
StressMark antibodies supplies antibodies that are for research of human proteins.
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Polyclonals and antibodies
Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.Rabbits are used for polyclonal antibody production by StressMark antibodies. Rabbit antibodies are very stable and can be stored for several days at room temperature. StressMark antibodies adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
Oryctolagus cuniculus