Immunogen
A phospho-specific peptide corresponding to residues surrounding Tyr217 and Ser218of human RSK3 (AA214-221)
Antibody's target
Human RSK3 (pTyr217 + pSer218)
Antibody's full description
Rabbit Anti-Human RSK3 (pTyr217 + pSer218) Polyclonal
100 µl
SPC-1080D-ALP
391€
A phospho-specific peptide corresponding to residues surrounding Tyr217 and Ser218of human RSK3 (AA214-221)
Human RSK3 (pTyr217 + pSer218)
Rabbit Anti-Human RSK3 (pTyr217 + pSer218) Polyclonal
Polyclonal Antibodies
RPS6KA2 Antibody, RSK 3 Antibody, RSK Antibody, RSK-3 Antibody, S6K alpha Antibody, S6K alpha 2 Antibody, S6K-alpha-2 Antibody, 90 kDa ribosomal protein S6 kinase 2 Antibody, Ribosomal protein S6 kinase alpha-2 Antibody, ribosomal protein S6 kinase, 90kDa, polypeptide 2 Antibody, Ribosomal S6 kinase 3 Antibody, HU 2 Antibody, KS6A2_HUMAN Antibody, MAP kinase activated protein kinase 1c Antibody, MAP kinase-activated protein kinase 1c Antibody, MAPK-activated protein kinase 1c Antibody, MAPKAP kinase 1c Antibody, MAPKAPK-1c Antibody, MAPKAPK1C Antibody, Mitogen.activated protein kinase-activated protein kinase 1C Antibody, p90 RSK3 Antibody, p90-RSK 2 Antibody, p90RSK2 Antibody, pp90RSK3 Antibody
WB, AM
Rabbit
Human
WB (1:250); optimal dilutions for assays should be determined by the user.
Peptide Affinity Purified
PBS pH7.4, 50% glycerol, 0.025% Thimerosal
See included datasheet or contact our support service
Detects 83.239 kDa.
-20°C
Blue Ice or 4°C
A 1:250 dilution of SPC-1080 was sufficient for detection of RSK3 (pTyr217 + pSer218) in 10 µg of HeLa cell lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
Nucleus, Cytoplasm
Widely expressed with higher expression in lung, skeletal muscle, brain, uterus, ovary, thyroid and prostate.
Serine/threonine-protein kinase that acts downstream of ERK (MAPK1/ERK2 and MAPK3/ERK1) signaling and mediates mitogenic and stress-induced activation of transcription factors, regulates translation, and mediates cellular proliferation, survival, and differentiation. May function as tumour suppressor in epithelial ovarian cancer cells.
Refer to PubMed
29/Aug/2016
NP_066958
6196
Q15349
Refer to PubMed
To be tested
To be tested
Contact our support service to receive datasheet or other technical documentation.
No Data Available
Non-hazardous
Canada
1.4
0.1
In Stock
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
StressMark antibodies supplies antibodies that are for research of human proteins.
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Polyclonals and antibodies
Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.Rabbits are used for polyclonal antibody production by StressMark antibodies. Rabbit antibodies are very stable and can be stored for several days at room temperature. StressMark antibodies adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
Oryctolagus cuniculus