Immunogen
A phospho-specific peptide corresponding to residues surrounding Thr211 of human NuaK1 (AA208-214)
Antibody's target
Human NuaK1 (pThr211)
Antibody's full description
Rabbit Anti-Human NuaK1 (pThr211) Polyclonal
100 µl
SPC-1036D-ALP
391€
A phospho-specific peptide corresponding to residues surrounding Thr211 of human NuaK1 (AA208-214)
Human NuaK1 (pThr211)
Rabbit Anti-Human NuaK1 (pThr211) Polyclonal
Polyclonal Antibodies
AMP activated protein kinase family member 5 antibody, AMPK related protein kinase 5 antibody, AMPK-related protein kinase 5 antibody, NUAK family SNF1 like kinase antibody, NUAK family SNF1-like kinase 1 antibody, Nuak1 antibody, NUAK1_HUMAN antibody
WB, AM
Rabbit
Human
WB (1:250); optimal dilutions for assays should be determined by the user.
Peptide Affinity Purified
PBS pH7.4, 50% glycerol, 0.025% Thimerosal
See included datasheet or contact our support service
Detects 74.305 kDa.
-20°C
Blue Ice or 4°C
A 1:250 dilution of SPC-1036 was sufficient for detection of NuaK1 (pThr211) in 10 µg of mouse brain lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
Nucleus, Cytoplasm
Expressed at high levels in heart and brain, and at lower levels in skeletal muscle, kidney, ovary, placenta, lung and liver.
NUAK1 is a protein-serine/threonine kinase. Involved in tolerance to glucose starvation. Phosphorylates ATM. Suppresses Fas-induced apoptosis by phosphorylation of CASP6, thus suppressing the activation of the caspase and the subsequent cleavage of CFLAR.
Refer to PubMed
29/Aug/2016
NP_055655
9891
O60285
Refer to PubMed
To be tested
To be tested
Contact our support service to receive datasheet or other technical documentation.
No Data Available
Non-hazardous
Canada
1.4
0.1
In Stock
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
StressMark antibodies supplies antibodies that are for research of human proteins.
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Polyclonals and antibodies
Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.Rabbits are used for polyclonal antibody production by StressMark antibodies. Rabbit antibodies are very stable and can be stored for several days at room temperature. StressMark antibodies adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
Oryctolagus cuniculus