Immunogen
A phospho-specific peptide corresponding to residues surrounding Ser31 of human LKB1 (STK11) (AA28-34)
Antibody's target
Human LKB1 (pSer31)
Antibody's full description
Rabbit Anti-Human LKB1 (pSer31) Polyclonal
100 µl
SPC-1008D-ALP
391€
A phospho-specific peptide corresponding to residues surrounding Ser31 of human LKB1 (STK11) (AA28-34)
Human LKB1 (pSer31)
Rabbit Anti-Human LKB1 (pSer31) Polyclonal
Polyclonal Antibodies
hLKB1 antibody, Liver kinase B1 antibody, LKB1 antibody, PJS antibody, Polarization related protein LKB1 antibody, Renal carcinoma antigen NY-REN-19 antibody, Serine/Threonine Kinase 11 antibody, Serine/threonine protein kinase STK11 antibody, Stk11 antibody, STK11_HUMAN antibody
WB, AM
Rabbit
Human
WB (1:250); optimal dilutions for assays should be determined by the user.
Peptide Affinity Purified
PBS pH7.4, 50% glycerol, 0.025% Thimerosal
See included datasheet or contact our support service
Detects 48.636 kDa.
-20°C
Blue Ice or 4°C
A 1:250 dilution of SPC-1008 was sufficient for detection of LKB1 (pSer31) in 10 µg of HeLa cell lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
Nucleus, Cytoplasm
Ubiquitously expressed. Strongest expression in testis and fetal liver.
LKB1 is a protein-serine/threonine kinase. Phosphorylates and activates AMP-activated kinase (AMPK), AMPK involved in stress responses, lipid and glucose metabolism. Its mutation pattern in human tumours is very characteristic of a tumour suppressor protein.
Refer to PubMed
29/Aug/2016
NP_000446
6794
Q15831
Refer to PubMed
To be tested
To be tested
Contact our support service to receive datasheet or other technical documentation.
No Data Available
Non-hazardous
Canada
1.4
0.1
In Stock
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
StressMark antibodies supplies antibodies that are for research of human proteins.
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Polyclonals and antibodies
Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.Rabbits are used for polyclonal antibody production by StressMark antibodies. Rabbit antibodies are very stable and can be stored for several days at room temperature. StressMark antibodies adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
Oryctolagus cuniculus