Immunogen
A phospho-specific peptide corresponding to residues surrounding Tyr156 and Thr157 of human ICK (AA152-158)
Antibody's target
Human ICK (pTyr156 + pThr157)
Antibody's full description
Rabbit Anti-Human ICK (pTyr156 + pThr157) Polyclonal
100 µl
SPC-996D-ALP
391€
A phospho-specific peptide corresponding to residues surrounding Tyr156 and Thr157 of human ICK (AA152-158)
Human ICK (pTyr156 + pThr157)
Rabbit Anti-Human ICK (pTyr156 + pThr157) Polyclonal
Polyclonal Antibodies
ECO Antibody, Heart serine threonine protein kinase Antibody, hICK Antibody, Intestinal cell (MAK like) kinase Antibody, Intestinal cell kinase Antibody, Laryngeal cancer kinase 2 Antibody, LCK2 Antibody, MAK related kinase Antibody, MGC46090 Antibody, mICK Antibody, MRK Antibody, Serine/threonine protein kinase ICK Antibody
WB, AM
Rabbit
Human
WB (1:250); optimal dilutions for assays should be determined by the user.
Peptide Affinity Purified
PBS pH7.4, 50% glycerol, 0.025% Thimerosal
See included datasheet or contact our support service
Detects 71.427 kDa.
-20°C
Blue Ice or 4°C
A 1:250 dilution of SPC-996 was sufficient for detection of ICK (pTyr156 + pThr157) in 10 µg of HeLa cell lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
Nucleus, Cytoplasm, Cytosol, Cytoskeleton
Expressed in heart, brain, placenta, pancreas, thymus, prostate, testis, ovary, small intestine and colon, with highest levels in placenta and testis. Not detected in spleen. Also expressed in many cancer cell lines
ICK1 encodes an intestinal serine/threonine kinase harboring a dual phosphorylation site found in mitogen-activating protein (MAP) kinases. The protein localizes to the intestinal crypt region and is thought to be important in intestinal epithelial cell proliferation and differentiation.
Refer to PubMed
29/Aug/2016
NP_055735
22858
Q9UPZ9
Refer to PubMed
To be tested
To be tested
Contact our support service to receive datasheet or other technical documentation.
No Data Available
Non-hazardous
Canada
1.4
0.1
In Stock
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
StressMark antibodies supplies antibodies that are for research of human proteins.
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Polyclonals and antibodies
Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.Rabbits are used for polyclonal antibody production by StressMark antibodies. Rabbit antibodies are very stable and can be stored for several days at room temperature. StressMark antibodies adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
Oryctolagus cuniculus