Immunogen
A phospho-specific peptide corresponding to residues surrounding Tyr387 of human FRK (AA384-390)
Antibody's target
Human FRK (pTyr387)
Antibody's full description
Rabbit Anti-Human FRK (pTyr387) Polyclonal
100 µl
SPC-984D-ALP
391€
A phospho-specific peptide corresponding to residues surrounding Tyr387 of human FRK (AA384-390)
Human FRK (pTyr387)
Rabbit Anti-Human FRK (pTyr387) Polyclonal
Polyclonal Antibodies
Beta cell Src homology tyrosine kinase Antibody, FRK Antibody, BSK Antibody, BSK/IYK Antibody, C85044 Antibody, Frk fyn related kinase Antibody, FRK_HUMAN Antibody, FYN related kinase Antibody, GASK Antibody, Gastrointestinal associated kinase Antibody, GTK Antibody, Intestine tyrosine kinase Antibody, Nuclear tyrosine protein kinase RAK Antibody, Protein-tyrosine kinase 5 Antibody, PTK5 Antibody, RAK Antibody,Tyrosine protein kinase FRK Antibody
WB, AM
Rabbit
Human
WB (1:250); optimal dilutions for assays should be determined by the user.
Peptide Affinity Purified
PBS pH7.4, 50% glycerol, 0.025% Thimerosal
See included datasheet or contact our support service
Detects 58.254 kDa.
-20°C
Blue Ice or 4°C
A 1:250 dilution of SPC-984 was sufficient for detection of FRK (pTyr387) in 10 µg of 293T cell lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
Cytoplasm, Nucleus
Highly expressed in epithelial derived cell lines and tissues, especially normal liver, kidney, breast and colon
FRK is a protein-tyrosine kinase. It is involved in positive regulation of PTEN by increasing its stability and preventing degradation and negative regulation of cell proliferation. It may also have functions during G1 and S phase in the nucleus to suppress growth.
Refer to PubMed
29/Aug/2016
NP_002022
2444
P42685
Refer to PubMed
To be tested
To be tested
Contact our support service to receive datasheet or other technical documentation.
No Data Available
Non-hazardous
Canada
1.4
0.1
In Stock
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
StressMark antibodies supplies antibodies that are for research of human proteins.
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Polyclonals and antibodies
Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.Rabbits are used for polyclonal antibody production by StressMark antibodies. Rabbit antibodies are very stable and can be stored for several days at room temperature. StressMark antibodies adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
Oryctolagus cuniculus