Immunogen
A phospho-specific peptide corresponding to residues surrounding Tyr713 and Ser716 of human FES (AA711-720)
Antibody's target
Human FES (pTyr713 + pSer716)
Antibody's full description
Rabbit Anti-Human FES (pTyr713 + pSer716) Polyclonal
100 µl
SPC-980D-ALP
391€
A phospho-specific peptide corresponding to residues surrounding Tyr713 and Ser716 of human FES (AA711-720)
Human FES (pTyr713 + pSer716)
Rabbit Anti-Human FES (pTyr713 + pSer716) Polyclonal
Polyclonal Antibodies
FPS Antibody, c-fes/fps protein Antibody, cFES Antibody, FES Antibody, Feline sarcoma (Snyder Theilen) viral (v fes)/Fujinami avian sarcoma (PRCII) viral (v fps) oncogene homolog Antibody, feline sarcoma (Snyder-Theilen) viral (v-fes)/Fujinami Antibody, Feline sarcoma oncogene Antibody, FES proto oncogene tyrosine kinase Antibody, FES_HUMAN Antibody, Oncogene FES Antibody, P93c fes Antibody, Proto oncogene tyrosine protein kinase, Fes/Fps Antibody, Proto-oncogene c-Fes Antibody, Proto-oncogene c-Fps Antibody, Tyrosine-protein kinase Fes/Fps Antibody
WB, AM
Rabbit
Human
WB (1:250); optimal dilutions for assays should be determined by the user.
Peptide Affinity Purified
PBS pH7.4, 50% glycerol, 0.025% Thimerosal
See included datasheet or contact our support service
Detects 93.471 kDa.
-20°C
Blue Ice or 4°C
A 1:250 dilution of SPC-980 was sufficient for detection of FES (pTyr713 + pSer716) in 10 µg of human placenta lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
Cell Junctions, Focal Adhesion, Cell Membrane, Cytoplasm, Cytosol, Golgi Apparatus
See included datasheet or contact our support service.
FES is a protein-tyrosine kinase is expressed in macrophages and is thought to be involved in the regulation of myeloid differentiation. Fes has several characteristics typical of a cytoplasmic class of protein tyrosine kinases, including an SH2 domain and autophosphorylation capabilities. Fes has been shown to associate with IL-4 and several hematopoietic cytokine receptors, as well as with BCR. Phosphorylation of BCR by Fes induces the association of BCR with the Ras guanine nucleotide exchange factor complex GRB2/Sos.
Refer to PubMed
29/Aug/2016
NP_001996
2243
P07332
Refer to PubMed
To be tested
To be tested
Contact our support service to receive datasheet or other technical documentation.
No Data Available
Non-hazardous
Canada
1.4
0.1
In Stock
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
StressMark antibodies supplies antibodies that are for research of human proteins.
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Polyclonals and antibodies
Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.Rabbits are used for polyclonal antibody production by StressMark antibodies. Rabbit antibodies are very stable and can be stored for several days at room temperature. StressMark antibodies adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
Oryctolagus cuniculus