Immunogen
A phospho-specific peptide corresponding to residues surrounding Tyr1289 of human ErbB3 (AA1286-1292)
Antibody's target
Human ErbB3 (pTyr1289)
Antibody's full description
Rabbit Anti-Human ErbB3 (pTyr1289) Polyclonal
100 µl
SPC-971D-ALP
391€
A phospho-specific peptide corresponding to residues surrounding Tyr1289 of human ErbB3 (AA1286-1292)
Human ErbB3 (pTyr1289)
Rabbit Anti-Human ErbB3 (pTyr1289) Polyclonal
Polyclonal Antibodies
c erbB3 Antibody, Erb b2 receptor tyrosine kinase 3 Antibody, ERBB3 Antibody, erbB3 S Antibody, ERBB3_HUMAN Antibody, Glial growth factor receptor Antibody, HER3 Antibody, Human epidermal growth factor receptor 3 Antibody, LCCS2 Antibody, MDA BF 1 Antibody, MGC88033 Antibody, p180 ErbB3 Antibody, p45 sErbB3 Antibody, p85 sErbB3 Antibody, proto-oncogene-like protein c ErbB3 Antibody, Receptor tyrosine protein kinase erbB3 Antibody, Tyrosine kinase type cell surface receptor HER3 Antibody, v erb b2 avian erythroblastic leukemia viral oncogene homolog 3 Antibody, v erb b2 erythroblastic leukemia viral oncogene homolog 3 Antibody
WB, AM
Rabbit
Human
WB (1:250); optimal dilutions for assays should be determined by the user.
Peptide Affinity Purified
PBS pH7.4, 50% glycerol, 0.025% Thimerosal
See included datasheet or contact our support service
Detects 148.098 kDa.
-20°C
Blue Ice or 4°C
A 1:250 dilution of SPC-971 was sufficient for detection of ErbB3 (pTyr1289) in 10 µg of HeLa cell lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
Cell Membrane, Secreted
Epithelial tissues and brain.
ErbB3 is a receptor tyrosine-protein kinase and a member of the epidermal growth factor receptor (EGFR) family. It will bind neuroligin ligand, but it lacks an active kinase domain; however, it will heterodimerize with EGFRs that do have kinase activity. Upregulation of this gene has been reported in numerous cancers.
Refer to PubMed
29/Aug/2016
NP_001973
2065
P21860
Refer to PubMed
To be tested
To be tested
Contact our support service to receive datasheet or other technical documentation.
No Data Available
Non-hazardous
Canada
1.4
0.1
In Stock
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
StressMark antibodies supplies antibodies that are for research of human proteins.
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Polyclonals and antibodies
Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.Rabbits are used for polyclonal antibody production by StressMark antibodies. Rabbit antibodies are very stable and can be stored for several days at room temperature. StressMark antibodies adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
Oryctolagus cuniculus