Immunogen
A phospho-specific peptide corresponding to residues surrounding Tyr588 of human EphA2 (AA585-591)
Antibody's target
Human EphA2 (pTyr588)
Antibody's full description
Rabbit Anti-Human EphA2 (pTyr588) Polyclonal
100 µl
SPC-966D-ALP
391€
A phospho-specific peptide corresponding to residues surrounding Tyr588 of human EphA2 (AA585-591)
Human EphA2 (pTyr588)
Rabbit Anti-Human EphA2 (pTyr588) Polyclonal
Polyclonal Antibodies
Eck antibody, Eph receptor A2 antibody, EPHA2 antibody, Ephrin receptor antibody, Ephrin receptor EphA2 antibody, Ephrin type A receptor 2 antibody, Epithelial cell kinase antibody, Myk 2 antibody, Sek 2 antibody, Tyrosine protein kinase receptor ECK antibody, Tyrosine-protein kinase receptor MPK-5 antibody, Tyrosine-protein kinase receptor SEK-2 antibody
WB, AM
Rabbit
Human
WB (1:250); optimal dilutions for assays should be determined by the user.
Peptide Affinity Purified
PBS pH7.4, 50% glycerol, 0.025% Thimerosal
See included datasheet or contact our support service
Detects 108.266 kDa.
-20°C
Blue Ice or 4°C
A 1:250 dilution of SPC-966 was sufficient for detection of EphA2 (pTyr588) in 10 µg of HepG2 cell lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
Membrane
Expressed in brain and glioma tissue and glioma cell lines (at protein level). Expressed most highly in tissues that contain a high proportion of epithelial cells, e.g., skin, intestine, lung, and ovary.
EphA2 is a receptor-tyrosine kinase that is activated upon binding ephrins of the ephrin A family. It regulates cell adhesion, migration, proliferation and differentiation. It also may be involved in apoptosis, induced by UV-radiation.
Refer to PubMed
29/Aug/2016
NP_004422
1969
P29317
Refer to PubMed
To be tested
To be tested
Contact our support service to receive datasheet or other technical documentation.
No Data Available
Non-hazardous
Canada
1.4
0.1
In Stock
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
StressMark antibodies supplies antibodies that are for research of human proteins.
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Polyclonals and antibodies
Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.Rabbits are used for polyclonal antibody production by StressMark antibodies. Rabbit antibodies are very stable and can be stored for several days at room temperature. StressMark antibodies adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
Oryctolagus cuniculus