Immunogen
A phospho-specific peptide corresponding to residues surrounding Tyr13 of human CDK6 (AA10-16)
Antibody's target
Human CDK6 (pTyr13)
Antibody's full description
Rabbit Anti-Human CDK6 (pTyr13) Polyclonal
100 µl
SPC-944D-ALP
391€
A phospho-specific peptide corresponding to residues surrounding Tyr13 of human CDK6 (AA10-16)
Human CDK6 (pTyr13)
Rabbit Anti-Human CDK6 (pTyr13) Polyclonal
Polyclonal Antibodies
CDK6_HUMAN Antibody, Cell division protein kinase 6 Antibody, Crk 2 Antibody, Cyclin dependent kinase 6 Antibody, PLSTIRE Antibody, Serine/threonine protein kinase PLSTIRE Antibody, STQTL11 Antibody
WB, AM
Rabbit
Human
WB (1:250); optimal dilutions for assays should be determined by the user.
Peptide Affinity Purified
PBS pH7.4, 50% glycerol, 0.025% Thimerosal
See included datasheet or contact our support service
Detects 36.938 kDa.
-20°C
Blue Ice or 4°C
A 1:250 dilution of SPC-944 was sufficient for detection of CDK6 (pTyr13) in 10 µg of Jurkat cell lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
Cytoplasmic
See included datasheet or contact our support service.
CDK6 is a protein-serine/threonine kinase. CDK6 is known to associate with cyclins D1, D2 and D3 and to be involved with the G1/S transition of the cell cycle. Multiple inhibitors of Cdk6 have been identified, including p18 and p19. These inhibitors bind to both free and complexed Cdk6, and they inhibit the activity of the cyclin D-bound Cdk6.
Refer to PubMed
29/Aug/2016
NP_001250
1021
Q00534
Refer to PubMed
To be tested
To be tested
Contact our support service to receive datasheet or other technical documentation.
No Data Available
Non-hazardous
Canada
1.4
0.1
In Stock
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
StressMark antibodies supplies antibodies that are for research of human proteins.
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Polyclonals and antibodies
Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.Rabbits are used for polyclonal antibody production by StressMark antibodies. Rabbit antibodies are very stable and can be stored for several days at room temperature. StressMark antibodies adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
Oryctolagus cuniculus