Immunogen
A phospho-specific peptide corresponding to residues surrounding Thr177 of human CaMK1 (AA174-180)
Antibody's target
Human CaMKI (pThr177)
Antibody's full description
Rabbit Anti-Human CaMKI (pThr177) Polyclonal
100 µl
SPC-930D-ALP
391€
A phospho-specific peptide corresponding to residues surrounding Thr177 of human CaMK1 (AA174-180)
Human CaMKI (pThr177)
Rabbit Anti-Human CaMKI (pThr177) Polyclonal
Polyclonal Antibodies
Calcium / calmodulin dependent protein kinase type 1 Antibody, CaM K1 Antibody, CaM kinase 1 alpha Antibody, CaM-KI Antibody, CaMK1 alpha Antibody, CaMKI-alpha Antibody, KCC1A_HUMAN Antibody
WB, AM
Rabbit
Human
WB (1:250); optimal dilutions for assays should be determined by the user.
Peptide Affinity Purified
PBS pH7.4, 50% glycerol, 0.025% Thimerosal
See included datasheet or contact our support service
Detects 41.337 kDa.
-20°C
Blue Ice or 4°C
A 1:250 dilution of SPC-930 was sufficient for detection of CaMKI (pThr177) in 10 µg of human brain lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
Cytoplasm, Nucleus
See included datasheet or contact our support service.
Calcium / calmodulin-dependent kinases (CaMKs) are a subfamily of the serine/threonine protein kinase family that includes CaMKI, CaMKII, and CaMKIV. There have been identified multiple substrates for CaMKI, including synapsin 1, synapsin 2, CREB, and CFTR, and its activation is dependent upon phosphorylation of Thr 177 by CaMK kinase (CaMKK). Studies suggest that CaMKI plays an important role in retinal function and its expression is regulated by light stimulation.
Refer to PubMed
29/Aug/2016
NP_003647
8536
Q14012
Refer to PubMed
To be tested
To be tested
Contact our support service to receive datasheet or other technical documentation.
No Data Available
Non-hazardous
Canada
1.4
0.1
In Stock
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
StressMark antibodies supplies antibodies that are for research of human proteins.
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Polyclonals and antibodies
Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.Rabbits are used for polyclonal antibody production by StressMark antibodies. Rabbit antibodies are very stable and can be stored for several days at room temperature. StressMark antibodies adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
Oryctolagus cuniculus