Immunogen
Peptide derived from human p62 protein UBA domain (a.a 387-436)
Antibody's target
Human p62
Antibody's full description
Rabbit Anti-Human p62 Polyclonal
100 µl
SPC-219D-ALP
381€
Peptide derived from human p62 protein UBA domain (a.a 387-436)
Human p62
Rabbit Anti-Human p62 Polyclonal
Cancer, Autophagy
Polyclonal Antibodies
SQSTM1 Antibody, EBIAP Antibody, p60 Antibody, Sequestosome-1 Antibody, Phosphotyrosine independent ligand for the Lck SH2 domain p62 antibody, Ubiquitin binding protein p62 antibody
WB
Rabbit
Human
WB (1:5000); optimal dilutions for assays should be determined by the user.
Salt precipitated
PBS, 0.1% sodium azide
See included datasheet or contact our support service
Ubiquitin binding autophagy receptor protein.
4°C
Blue Ice or 4°C
A 1:500 dilution of SPC-219 was sufficient for detection of p62 in human spleen tissue lysate by electrochemiluminescence analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
Cytoplasm, Cytoplasmic Vesicle, Autophagosome, Endosome, Late Endosome, Nucleus, Endoplasmic Reticulum
See included datasheet or contact our support service.
p62 is a scaffolding adaptor protein which is expressed under conditions of cellular stress. This protein has a variety of protein binding domains, allowing it to regulate a variety of signal transduction pathways. It also has an influence on protein trafficking, aggregation and degradation. p62 plays an important role in mediating autophagy.
1. Wang L., Cano M., & Handa J. (2014) Biochim Biophys Acta. 1843(7): 1248-58.
12/Jun/2014
NP_714941.10
8887
Q13510
Refer to PubMed
To be tested
To be tested
Contact our support service to receive datasheet or other technical documentation.
No Data Available
Non-hazardous
Canada
1.4
0.1
In Stock
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
StressMark antibodies supplies antibodies that are for research of human proteins.
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Polyclonals and antibodies
Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.Rabbits are used for polyclonal antibody production by StressMark antibodies. Rabbit antibodies are very stable and can be stored for several days at room temperature. StressMark antibodies adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
Oryctolagus cuniculus
