Synonym
Fructose-1;6-Bisphosphatase 1; FBPase 1; D-Fructose-1;6-Bisphosphate 1-Phosphohydrolase 1; FBP1; FBP
Activity
NA
Sequence
Ala2-Gln338
10µg
PKSH033276-10µg
190€
Fructose-1;6-Bisphosphatase 1; FBPase 1; D-Fructose-1;6-Bisphosphate 1-Phosphohydrolase 1; FBP1; FBP
NA
Ala2-Gln338
C-6His
P09467
E.coli
The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
＞85% as determined by reducing SDS-PAGE.
＜1.0 EU per µg as determined by LAL test.
Store at < -20℃, stable for 6 monthshs after receipt.Please minimize freeze-thaw cycles
37.9 kDa
38 kDa
Supplied as a 0.2 μm filtered solution of 20mM TrisHCl, 200mM NaCl, 1mM DTT, 1mM EDTA, 20% Glycerol, pH 8.0.
Fructose-1,6-Bisphosphatase 1 (FBPase 1) is a member of the FBPase class 1 family. FBPase 1 is a gluconeogenesis regulatory protein, which catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. FBPase 1 can assume an active R-state, or an inactive T-state. FBPase 1 deficiency is inherited as an autosomal recessive disorder mainly in the liver and causes life-threatening episodes of hypoglycemia and metabolic acidosis in newborn infants or young children. FBPase 1 coupled with phosphofructokinase (PFK) is involved in the metabolism of pancreatic islet cells.
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Recombinants or rec. proteins
recombinants
