Size

50µg

Catalog No

PKSH033276-50µg

Price

351€

Buy: Recombinant Human Fructose-1,6-Bisphosphatase 1/FBPase 1 Protein(E. coli, C-6His) 50µg

Synonym

Fructose-1;6-Bisphosphatase 1; FBPase 1; D-Fructose-1;6-Bisphosphate 1-Phosphohydrolase 1; FBP1; FBP

Activity

NA

Sequence

Ala2-Gln338

Fusion tag

C-6His

Accession

P09467

Expressed Host

E.coli

Shipping

The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.

Purity

＞85% as determined by reducing SDS-PAGE.

Endotoxin

＜1.0 EU per µg as determined by LAL test.

Stability and Storage

Store at < -20℃, stable for 6 monthshs after receipt.Please minimize freeze-thaw cycles

Mol Mass

37.9 kDa

AP Mol Mass

38 kDa

Formulation

Supplied as a 0.2 μm filtered solution of 20mM TrisHCl, 200mM NaCl, 1mM DTT, 1mM EDTA, 20% Glycerol, pH 8.0.

Reconstitution

Please refer to it for detailed information.

Background

Fructose-1,6-Bisphosphatase 1 (FBPase 1) is a member of the FBPase class 1 family. FBPase 1 is a gluconeogenesis regulatory protein, which catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. FBPase 1 can assume an active R-state, or an inactive T-state. FBPase 1 deficiency is inherited as an autosomal recessive disorder mainly in the liver and causes life-threatening episodes of hypoglycemia and metabolic acidosis in newborn infants or young children. FBPase 1 coupled with phosphofructokinase (PFK) is involved in the metabolism of pancreatic islet cells.

Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

Source

Recombinants or rec. proteins

Group

recombinants