Synonym
Inositol Monophosphatase 1; IMP 1; IMPase 1; Inositol-1(or 4)-Monophosphatase 1; Lithium-Sensitive Myo-Inositol Monophosphatase A1; IMPA1; IMPA
Activity
NA
Sequence
Met1-Asp277
10µg
PKSH032590-10µg
267€
Inositol Monophosphatase 1; IMP 1; IMPase 1; Inositol-1(or 4)-Monophosphatase 1; Lithium-Sensitive Myo-Inositol Monophosphatase A1; IMPA1; IMPA
NA
Met1-Asp277
N-6His
P29218
E.coli
The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
＞95% as determined by reducing SDS-PAGE.
＜1.0 EU per µg as determined by LAL test.
Store at < -20℃, stable for 6 monthshs after receipt.Please minimize freeze-thaw cycles
32.3 kDa
30 kDa
Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.25.
Inositol Monophosphatase 1 (IMPA1) belongs to the inositol monophosphatase family. IMPA1 is responsible for the provision of inositol required for synthesis of phosphatidylinositol and polyphosphoinositides, IMPA1 can use myo-inositol-1,3-diphosphate, myo-inositol-1,4-diphosphate, scyllo-inositol-phosphate, glucose-1-phosphate, glucose-6-phosphate, fructose-1-phosphate, beta-glycerophosphate, and 2-AMP as substrates. IMPA1 has been implicated as the pharmacological target for lithium action in brain. IMPA1 shows magnesium-dependent phosphatase activity and is inhibited by therapeutic concentrations of lithium. In addition, IMPA1 plays a improtant role in intracellular signal transduction.
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Recombinants or rec. proteins
recombinants
