Synonym
6-phosphofructo-2-kinase/fructose-2;6-bisphosphatase 1; 6PF-2-K/Fru-2;6-P2ase liver isozyme; Fructose-2;6-bisphosphatase; PFKFB1; F6PK; PFRX
Activity
NA
Sequence
Ser2-Tyr471
10µg
PKSH032459-10µg
267€
6-phosphofructo-2-kinase/fructose-2;6-bisphosphatase 1; 6PF-2-K/Fru-2;6-P2ase liver isozyme; Fructose-2;6-bisphosphatase; PFKFB1; F6PK; PFRX
NA
Ser2-Tyr471
C-6His
P16118
Human cells
The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
＞95% as determined by reducing SDS-PAGE.
＜1.0 EU per µg as determined by LAL test.
Store at < -20℃, stable for 6 monthshs after receipt.Please minimize freeze-thaw cycles
55.6 kDa
60 kDa
Supplied as a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 is an enzyme that in humans is encoded by the PFKFB1 gene. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. It belongs to the phosphoglycerate mutase family. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis.
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Recombinants or rec. proteins
recombinants
