Recombinant Human ACP5 / TRAP Protein (His tag)

Size

10µg

Catalog No

PKSH031534-10µg

Price

356€

Synonym

SPENCDI;TRAP

Activity

NA

Sequence

Met 1-Pro 320

Recombinant Human ACP5 / TRAP Protein (His tag)

Fusion tag

C-His

Accession

NP_001602.1

Expressed Host

HEK293 Cells

Recombinant Human ACP5 / TRAP Protein (His tag)

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.

Purity

>95 % as determined by SDS-PAGE

Endotoxin

<1.0 EU per µg as determined by the LAL method

Recombinant Human ACP5 / TRAP Protein (His tag)

Stability and Storage

Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

Mol Mass

35 kDa

AP Mol Mass

35 kDa

Recombinant Human ACP5 / TRAP Protein (His tag)

Formulation

Lyophilized from sterile PBS, pH 7.4

Background

Tartrate-resistant acid phosphatase (TRACP) or acid phosphatase 5, tartrate resistant (ACP5 or TRAP) is a glycosylated monomeric metalloenzyme expressed in mammals. TRACP is associated with osteoblast migration to bone resorption sites, and, once there, TRACP is believed to initiate osteoblast differentiation, activation, and proliferation. TRACP once considered to be just a histochemical marker of osteoclasts is now recognised to be a molecule of widespread occurrence with functions in both the skeleton and the immune system. Two forms of TRACP circulate in human blood, TRACP 5a derived from macrophages and dendritic cells, and TRACP-5b derived from osteoclasts. Recent data have demonstrated the utility of TRACP-5b as a marker of osteoclast number and bone resorption, and serum TRACP-5a as a marker of inflammatory conditions. TRACP is expressed by osteoclasts, macrophages, dendritic cells and a number of other cell types. It has a critical role in many biological processes including skeletal development, collagen synthesis and degradation, the mineralisation of bone, cytokine production by macrophages and dendritic cells, macrophage recruitment, dendritic cell maturation and a role in the development of Th1 responses.

Conjugation

histidine

Recombinant Human ACP5 / TRAP Protein (His tag)

Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

Source

Recombinants or rec. proteins

Group

recombinants

Recombinant Human ACP5 / TRAP Protein (His tag)
Recombinant Human ACP5 / TRAP Protein (His tag)