PPP1R13L (RelA-associated Inhibitor, Inhibitor of ASPP Protein, Protein iASPP, NFkB-interacting Protein 1, PPP1R13B-like Protein, IASPP, NKIP1, PPP1R13BL, RAI)[PPP1R13L]

Products_type

Antibody

Reactivity

Human

Description

Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.

PPP1R13L (RelA-associated Inhibitor, Inhibitor of ASPP Protein, Protein iASPP, NFkB-interacting Protein 1, PPP1R13B-like Protein, IASPP, NKIP1, PPP1R13BL, RAI)[PPP1R13L]

Gene

NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) is a protein complex that controls transcription of DNA, cytokine production and cell survival. NF-κB is found in almost all animal cell types and is involved in cellular responses to stimuli such as stress, cytokines, free radicals, ultraviolet irradiation, oxidized LDL, and bacterial or viral antigens. NF-κB plays a key role in regulating the immune response to infection (κ light chains are critical components of immunoglobulins). Incorrect regulation of NF-κB has been linked to cancer, inflammatory and autoimmune diseases, septic shock, viral infection, and improper immune development. NF-κB has also been implicated in processes of synaptic plasticity and memory

PPP1R13L (RelA-associated Inhibitor, Inhibitor of ASPP Protein, Protein iASPP, NFkB-interacting Protein 1, PPP1R13B-like Protein, IASPP, NKIP1, PPP1R13BL, RAI)[PPP1R13L]